Palmarplantar keratodermas
نویسندگان
چکیده
منابع مشابه
Palmoplantar keratodermas: clinical and genetic aspects.
Palmoplantar keratodermas comprise a diverse group of acquired and hereditary disorders marked by excessive thickening of the epidermis of palms and soles. Early onset and positive family history suggest a genetic cause. While hereditary forms of palmoplantar keratoderma (PPK) may represent the sole or dominant clinical feature, they may also be associated with other ectodermal defects or extra...
متن کاملKeratinization Disorders and Genetic Aspects in Palmar and Plantar Keratodermas.
Palmoplantar keratoderma (PPK) is a heterogeneous group of hereditary and acquired disorders characterized by abnormal thickening of the palms and soles. There are three clinical patterns: diffuse, focal, and punctuate. Palmoplantar keratodermas can be divided into the following functional subgroups: disturbed gene functions in structural proteins (keratins), cornified envelope (loricrin, trans...
متن کاملLoricrin and human skin diseases: molecular basis of loricrin keratodermas.
The cornified cell envelope (CE) is a tough structure formed beneath the plasma membrane of terminally differentiated keratinocytes. Recent progress in understanding the molecular organization of the CE has disclosed the complex, yet orderly structure that functions as a protective barrier against the environment. We have recently demonstrated that two inherited skin diseases, Vohwinkel's syndr...
متن کاملPunctate Palmoplantar Keratodermas: Case Reports and A Review of the Literature and Terminology
Keratodermas encompass a wide spectrum of disorders of keratinization that may be acquired or hereditary. We present two cases of focal acral hyperkeratosis (FAH), a subtype of punctate palmoplantar keratoderma. We review the literature and attempt to clarify the confusing classification of the heritable punctate palmoplantar keratodermas.
متن کاملUnique autosomal recessive variant of palmoplantar keratoderma associated with hearing loss not caused by known mutations*
Inherited Palmoplantar Keratodermas are rare disorders of genodermatosis that are conventionally regarded as autosomal dominant in inheritance with extensive clinical and genetic heterogeneity. This is the first report of a unique autosomal recessive Inherited Palmoplantar keratoderma -sensorineural hearing loss syndrome which has not been reported before in 3 siblings of a large consanguineous...
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ژورنال
عنوان ژورنال: The Medicine Forum
سال: 2007
ISSN: 2325-2863
DOI: 10.29046/tmf.009.1.004